杨四海 教授

办公地址：生科大楼B418

电话：+86-025-89686406

传真：+86-025-83592705

E-mail: sihaiyang(at)nju.edu.cn

      Yang S, Wang L, Huang J, Zhang X, Yuan Y, Chen J-Q, Hurst LD*, Tian D* (2015). Parent-progeny sequencing indicates higher mutation rates in heterozygotes. Nature 523: 463–467

      Zhang X#, Yang S#, Wang J#, Jia Y#, Huang J#, Zhong Y, Tan S, Wang L, Gu L, Chen JQ, Pan QH*, Bergelson J*, Tian D* (2015). A genome-wide survey reveals abundant rice blast R-genes in resistant cultivars. Plant J 84 :20-28 (IF5y =6.963)

      Liu H#, Zhang X#, Huang J, Chen JQ, Tian D, Hurst LD*, Yang S*. (2015) Causes and consequences of crossing-over evidenced via a high-resolution recombinational landscape of the honey bee. Genome Biology 16:15（IF5y=13.48)

      Si W, Yuan Y, Huang J, Zhang X, Zhang Y, Zhang Y, Tian D, Wang C, Yang YH*, Yang S*. (2015) Widely distributed hot and cold spots in meiotic recombination as shown by sequencing of rice F2 plants. New Phytologist 206 :1491-1502 (IF5y =7.837)

      Guo C, Sun X, Chen X, Yang S, Li J, Wang L, Zhang X. (2015) Novel rice blast resistance genes cloning from two rapidly evolving NBS-LRR gene families in rice. Plant Mol Biol 90: 95-105

      Li J, Zhou J, Wu, Y, Yang S, Tian D*. (2015) GC-content of synonymous codons profoundly infulences amino acid usage. G3 : Genes|Genomes|Genetics 5(10):2027-36

      Zhao L, Zhang Q, Gao R, Yang S, Liu H, Zhang X. (2015) High genetic abundance of Rpi-blb2/Mi-1.2/Cami gene family in Solanaceae. BMC Evol Biol 15:215

      Gu L, Si W, Zhao L, Yang S*, Zhang X*. (2015) Dynamic evolution of NBS-LRR genes in bread wheat and its progenitors. Mol Genet Genomics 290:727-738

      Jia Y, Yuan Y. Zhang Y. Yang S*, Zhang X*. (2015) Extreme expansion of NBS-encoding genes in Rosaceae. BMC Genetics 16 : 48

      Xie Z, Si W, Gao R, Zhang X*, Yang S*. (2015) Ancient origins and rapid evolution of RB/Rpi-blb1 locus in Solanaceae. Mol Genet Genomics DOI: 10.1007/s00438-015-1068-9

      Liu H, Xie Z, Tan S, Zhang X*, Yang S* (2015) Relationship between Amino Acid Usage and Amino Acid Evolution in Primates. Gene 557: 182-187

      Huang J, Si W, Deng Q, Li P*, Yang S*. (2014) Rapid evolution of avirulence genes in rice blast fungus Magnaporthe oryzae. BMC Genetics 15:45

      Wang D, Guo CJ, Huang J, Yang S, Tian D*, Zhang X*. (2014) Allele-mining of rice blast resistance genes at AC134922 locus. BBRC 446(4):1085-90

      Yang S, Li J, Zhang X, Zhang Q, Huang J, Chen J-Q, Hartl DL, Tian D*. (2013) Rapidly evolving R genes in diverse grass species confer resistance to rice blast disease. Proc Natl Acad Sci U S A 110: 18572-18577.

      Zhong Y, Jia Y, Gao Y, Tian D, Yang S*, Zhang X*. (2013) Functional requirements driving the gene duplication in 12 Drosophila species. BMC Genomics 14:555.

      Yang S, Yuan Y, Wang L, Li J, Wang W, Liu H, Chen JQ, Hurst LD, Tian D*. (2012) Great majority of recombination events in Arabidopsis are gene conversion events. Proc Natl Acad Sci U S A 109: 20992–20997.

      Yue J-X, Meyers BC, Chen J-Q, Tian D*, Yang S*. (2012) Tracing the origin and evolutionary history of plant nucleotide-binding site-leucine-rich repeat (NBS-LRR) genes. New Phytologist 193: 1049–1063.

      Tan S, Zhong Y, Hou H, Yang S*, Tian D*.. (2012) Variation of presence/absence genes among Arabidopsis populations. BMC Evol Biol 12:86.

      Wang L, Si W, Yao Y, Tian D, Araki H. Yang S*. (2012) Genome-wide survey of pseudogenes in 80 fully re-sequenced Arabidopsis thaliana accessions. Plos One 7(12): e51769.

      Wu K, Xu T, Guo C, Zhang X, Yang S*. (2012) Heterogeneous evolutionary rates of Pi2/9 genes in rice lines BMC Genetics 13:73.

      Li L, Memon S, Fan Y, Yang S*, Tan S. (2012) Recent duplications drive the rapid diversification of trypsin genes in 12 Drosophila. Genetica 140: 297-305.

      Tan S, Wang D, Ding J, Tian D, Zhang XH, Yang S*. (2011) Adaptive evolution of Xa21 homologs in gramineae. Genetica 139:1465-1475.

      Zhang X, Wang L, Yuan Y, Tian D*, Yang S*. (2011) Rapid copy number expansion and recent recruitment of domains in S-receptor kinase-like genes contribute to the origin of self-incompatibility. FEBS J 278: 4323-4337.

      Zhang X, Feng Y, Chen H, Tian D, Yang S*, Chen J-Q*. (2011) Relative evolutionary rates of NBS-encoding genes revealed by soybean segmental duplication.Mol Genet Genomics 285: 79-90.

      Yue J-X, Li J, Wang D, Araki H, Tian D, Yang S*. (2010) Genome-wide investigation reveals high evolutionary rates in annual model plants. BMC Plant Biol 10: 242.

      Li J, Ding J, Zhang W, Zhang Y, Tang P, Chen JQ, Tian D*, Yang S*. (2010) Unique evolutionary pattern of numbers of gramineous NBS-LRR genes. Mol Genet Genomics 283:427–438.

      Chen Q, Han Z, Jiang H, Tian D*, Yang S*. (2010) Strong Positive Selection Drives Rapid Diversification of R-Genes in Arabidopsis Relatives. J Mol Evol 70: 137-148.

      Tang P, Zhang Y, Sun X, Tian D, Yang S*, Ding J*. (2010) Disease resistance signature of the leucine-rich repeat receptor-like kinase genes in four plant species. Plant Sci 179: 399-406.

      Zhang Y, Wang J, Zhang X, Chen JQ, Tian D*, Yang S*. (2009) Genetic Signature of Rice Domestication Shown by a Variety of Genes. J Mol Evol 68: 393-402.

      Yang H, Wu Y, Feng J, Yang S*, Tian D*. (2009) Evolutionary pattern of protein architecture in mammal and fruit fly genomes. Genomics 93: 90-97.

      Zhu L, Zhang Y, Zhang W, Yang S*, Chen J-Q, Tian D. (2009) Patterns of exon-intron architecture variation of genes in eukaryotic genomes. BMC Genomics 10:47.

      Tian D*, Wang Q, Zhang P, Araki H, Yang S, Kreitman M, Nagylaki T, Hudson T, Bergelson J, Chen J*. (2008) Single-nucleotide mutation rate increases close to insertions/deletions in eukaryotes. Nature 455: 105-108.

      Yang S, Gu T., Pan C., Feng Z., Ding J., Hang Y., Chen J., Tian D*. (2008) Genetic variation of NBS-LRR class resistance genes in rice lines. Theor Appl Genet. 116: 165-177.

      Yang S, Zhang X, Yue J-X, Tian D, Chen J-Q*. (2008) Recent duplications dominate NBS-encoding gene expansion in two woody species. Mol Genet Genomics 280: 187-198.

      Sun X, Zhang Y, Yang S, Chen JQ, Hohn B and Tian D*. (2008) Insertion DNA promotes ectopic recombination during meiosis in Arabidopsis. Mol Biol Evol 25: 2079-2083.

      Yang S, Jiang K, Araki H, Ding J, Yang Y-H, Tian D*. (2007) A molecular isolation mechanism associated with high intra-specific diversity in rice. Gene 394: 87-95.

      Jiang H, Wang C, Ping L, Tian D*, Yang S*. (2007) Pattern of LRR nucleotide variation in plant resistance genes. Plant science 173: 253-261.

      Ding J, Araki H, Wang Q, Zhang P, Yang S, Chen J-Q*, Tian D*. (2007) Highly asymmetric rice genomes. BMC Genomics 8: 154.

      Yang S, Feng Z, Zhang X, Jiang K, Jin X, Hang Y, Chen J-Q, Tian D*. (2006) Genome-wide investigation on the genetic variations of rice disease resistance genes. Plant Mol Biol 62: 181-192.